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金ナノ粒子および幹細胞を併用した滅菌および皮膚創傷治療応用へのin-vitro研究

研究課題

産学が連携した研究開発成果の展開 研究成果展開事業 研究成果最適展開支援プログラム(A-STEP) 探索タイプ

研究責任者 Dakrong Pissuwan  大阪大学, 免疫学フロンティア研究センター, 特任研究員(常勤)
研究期間 (年度) 2013
概要The oil base formulation of gold nanorods with and withoutantibacterial peptides were prepared and characterized. Following this, the formulations were applied to resistant antibiotic bacteria (S. aureus MRSA) with laser irradiation at a near infrar ed wavelength (NIR). The results show that the complex of gold nanorod-antibacterial peptide in an oil base formulation (GNR/ abp/O) could decrease the cell viability of bacteria to around 53.4%. The results from my investigation of penetration of GNRs in a form of GNR/abp/O through the mouse skin, imply that GNR/abp/O formulation applied with laser irradiation could have a potential to destroy bacteria on the skin surface and may also be effective in the deeper areas of the skin.

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JSTプロジェクトデータベース掲載開始日: 2016-04-26   JSTプロジェクトデータベース最終更新日: 2025-03-26  

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